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Evaluating the within-host fitness effects of mutations fixed during virus adaptation to different ecotypes of a new host

The existence of genetic variation for resistance in host populations is assumed to be essential to the spread of an emerging virus. Models predict that the rate of spread slows down with the increasing frequency and higher diversity of resistance alleles in the host population. We have been using t...

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Dades bibliogràfiques
Publicat a:Philos Trans R Soc Lond B Biol Sci
Autors principals: Hillung, Julia, Cuevas, José M., Elena, Santiago F.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528490/
https://ncbi.nlm.nih.gov/pubmed/26150658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0292
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