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Evaluating the within-host fitness effects of mutations fixed during virus adaptation to different ecotypes of a new host

The existence of genetic variation for resistance in host populations is assumed to be essential to the spread of an emerging virus. Models predict that the rate of spread slows down with the increasing frequency and higher diversity of resistance alleles in the host population. We have been using t...

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Vydáno v:Philos Trans R Soc Lond B Biol Sci
Hlavní autoři: Hillung, Julia, Cuevas, José M., Elena, Santiago F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528490/
https://ncbi.nlm.nih.gov/pubmed/26150658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0292
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