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Effects of neutralizing antibodies on escape from CD8(+) T-cell responses in HIV-1 infection

Despite substantial advances in our knowledge of immune responses against HIV-1 and of its evolution within the host, it remains unclear why control of the virus eventually breaks down. Here, we present a new theoretical framework for the infection dynamics of HIV-1 that combines antibody and CD8(+)...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: Wikramaratna, Paul S., Lourenço, José, Klenerman, Paul, Pybus, Oliver G., Gupta, Sunetra
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528488/
https://ncbi.nlm.nih.gov/pubmed/26150656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0290
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