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The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains

The human and mouse antibody repertoires are formed by identical processes, but like all small animals, mice only have sufficient lymphocytes to express a small part of the potential antibody repertoire. In this study, we determined how the heavy chain repertoires of two mouse strains are generated....

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Podrobná bibliografie
Vydáno v:Philos Trans R Soc Lond B Biol Sci
Hlavní autoři: Collins, Andrew M., Wang, Yan, Roskin, Krishna M., Marquis, Christopher P., Jackson, Katherine J. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528413/
https://ncbi.nlm.nih.gov/pubmed/26194750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0236
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