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The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains
The human and mouse antibody repertoires are formed by identical processes, but like all small animals, mice only have sufficient lymphocytes to express a small part of the potential antibody repertoire. In this study, we determined how the heavy chain repertoires of two mouse strains are generated....
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| Veröffentlicht in: | Philos Trans R Soc Lond B Biol Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528413/ https://ncbi.nlm.nih.gov/pubmed/26194750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0236 |
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