TGFβ-activated Kinase 1 (TAK1) Inhibition by 5Z-7-Oxozeaenol Attenuates Early Brain Injury after Experimental Subarachnoid Hemorrhage

Accumulating evidence suggests that activation of mitogen-activated protein kinases (MAPKs) and nuclear factor NF-κB exacerbates early brain injury (EBI) following subarachnoid hemorrhage (SAH) by provoking proapoptotic and proinflammatory cellular signaling. Here we evaluate the role of TGFβ-activa...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Dingding, Yan, Huiying, Li, Hua, Hao, Shuangying, Zhuang, Zong, Liu, Ming, Sun, Qing, Yang, Yiqing, Zhou, Mengliang, Li, Kuanyu, Hang, Chunhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528149/
https://ncbi.nlm.nih.gov/pubmed/26100626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.636795
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