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Three protein factors (SF1, SF3 and U2AF) function in pre-splicing complex formation in addition to snRNPs.

The splicing of nuclear messenger RNA precursors can be reproduced in vitro with fractions obtained after chromatography of HeLa cell nuclear extracts. Here we report the chromatographic separation of three protein factors: SF1, SF3 and U2AF. All factors function early in the splicing reaction, in t...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Krämer, A, Utans, U
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1827409/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07670.x
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