Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220

The proximity of an enzyme to its substrate can influence rate and magnitude of catalysis. A-kinase anchoring protein 220 (AKAP220) is a multivalent anchoring protein that can sequester a variety of signal transduction enzymes. These include protein kinase A (PKA) and glycogen synthase kinase 3β (GS...

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Vydáno v:J Biol Chem
Hlavní autoři: Whiting, Jennifer L., Nygren, Patrick J., Tunquist, Brian J., Langeberg, Lorene K., Seternes, Ole-Morten, Scott, John D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528109/
https://ncbi.nlm.nih.gov/pubmed/26088133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654822
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