Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure

C3 exoenzyme is a mono-ADP-ribosyltransferase (ART) that catalyzes transfer of an ADP-ribose moiety from NAD(+) to Rho GTPases. C3 has long been used to study the diverse regulatory functions of Rho GTPases. How C3 recognizes its substrate and how ADP-ribosylation proceeds are still poorly understoo...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Toda, Akiyuki, Tsurumura, Toshiharu, Yoshida, Toru, Tsumori, Yayoi, Tsuge, Hideaki
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528107/
https://ncbi.nlm.nih.gov/pubmed/26067270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.653220
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