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Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus

In the last hundred years, four influenza pandemics have been experienced, beginning with that in Spain in 1918. Influenza A virus causes severe pneumonia and its RNA polymerase is an important target for drug design. The influenza A (H1N1) virus has eight ribonucleoprotein complexes, which are comp...

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Bibliographische Detailangaben
Hauptverfasser: Tsurumura, Toshiharu, Qiu, Hao, Yoshida, Toru, Tsumori, Yayoi, Tsuge, Hideaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943113/
https://ncbi.nlm.nih.gov/pubmed/24419622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X13032603
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