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Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
Clostridium perfringens iota-toxin (Ia) mono-ADP ribosylates Arg177 of actin, leading to cytoskeletal disorganization and cell death. To fully understand the reaction mechanism of arginine-specific mono-ADP ribosyl transferase, the structure of the toxin-substrate protein complex must be characteriz...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600452/ https://ncbi.nlm.nih.gov/pubmed/23382240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217227110 |
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