Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens ι-toxin

The ADP-ribosylating toxins (ADPRTs) produced by pathogenic bacteria modify intracellular protein and affect eukaryotic cell function. Actin-specific ADPRTs (including Clostridium perfringens ι-toxin and Clostridium botulinum C2 toxin) ADP-ribosylate G-actin at Arg-177, leading to disorganization of...

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Main Authors: Tsuge, Hideaki, Nagahama, Masahiro, Oda, Masataka, Iwamoto, Shinobu, Utsunomiya, Hiroko, Marquez, Victor E., Katunuma, Nobuhiko, Nishizawa, Mugio, Sakurai, Jun
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387182/
https://ncbi.nlm.nih.gov/pubmed/18490658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801215105
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