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Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach

The mechanism of action of the widely used in vivo ferric chloride (FeCl(3)) thrombosis model remains poorly understood; although endothelial cell denudation is historically cited, a recent study refutes this and implicates a role for erythrocytes. Given the complexity of the in vivo environment, an...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Ciciliano, Jordan C., Sakurai, Yumiko, Myers, David R., Fay, Meredith E., Hechler, Beatrice, Meeks, Shannon, Li, Renhao, Dixon, J. Brandon, Lyon, L. Andrew, Gachet, Christian, Lam, Wilbur A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528067/
https://ncbi.nlm.nih.gov/pubmed/25931587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-628594
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