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Vascular smooth muscle–derived tissue factor is critical for arterial thrombosis after ferric chloride–induced injury

Tissue factor (TF) initiates coagulation, regulates hemostasis, and plays a critical role in mediating arterial thrombosis. TF is up-regulated in vascular smooth muscle cells (VSMCs) in atherosclerosis and arterial injury. To examine the biologic role of VSMC-derived TF, we crossed TF(flox/flox) mic...

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Detalhes bibliográficos
Main Authors: Wang, Li, Miller, Christine, Swarthout, Robert F., Rao, Mohan, Mackman, Nigel, Taubman, Mark B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628377/
https://ncbi.nlm.nih.gov/pubmed/18931346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-090944
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