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Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer

The Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) is an estrogen receptor (ER) coactivator and a proto-oncogene known to be deregulated in endocrine cancers. In breast cancer, PELP1 overexpression has been associated with endocrine therapy resistance. Although PELP1 is known to be regu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Flågeng, Marianne Hauglid, Knappskog, Stian, Gjerde, Jennifer, Lønning, Per Eystein, Mellgren, Gunnar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527840/
https://ncbi.nlm.nih.gov/pubmed/26247365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134351
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