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Inverse Regulation of EGFR/HER1 and HER2-4 in Normal and Malignant Human Breast Tissue

Cross-talk between the estrogen and the EGFR/HER signalling pathways has been suggested as a potential cause of resistance to endocrine therapy in breast cancer. Here, we determined HER1-4 receptor and neuregulin-1 (NRG1) ligand mRNA expression levels in breast cancers and corresponding normal breas...

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Detalhes bibliográficos
Main Authors: Flågeng, Marianne Hauglid, Knappskog, Stian, Haynes, Ben P., Lønning, Per Eystein, Mellgren, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750010/
https://ncbi.nlm.nih.gov/pubmed/23991224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074618
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