Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2

Nociceptin/orphanin FQ (N/OFQ) controls several biological functions by selectively activating an opioid like receptor named N/OFQ peptide receptor (NOP). Biased agonism is emerging as an important and therapeutically relevant pharmacological concept in the field of G protein coupled receptors inclu...

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Bibliographic Details
Published in:PLoS One
Main Authors: Malfacini, D., Ambrosio, C., Gro’, M. C., Sbraccia, M., Trapella, C., Guerrini, R., Bonora, M., Pinton, P., Costa, T., Calo’, G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527783/
https://ncbi.nlm.nih.gov/pubmed/26248189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132865
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