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Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the β-catenin signaling activity
β-Catenin is a critical transducer of the Wnt signal pathway and plays an important role in many developmental and cellular processes. Deregulation of β-catenin signaling has been observed in a broad range of human tumors. In this report, we investigated whether tyrosine kinase inhibitor STI-571 cou...
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| Pubblicato in: | Cancer Lett |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527752/ https://ncbi.nlm.nih.gov/pubmed/12706873 |
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