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Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization
A limited repertoire of PPP family of serine/threonine phosphatases with a highly conserved catalytic domain acts on thousands of protein targets to orchestrate myriad central biological roles. A major structural reorganization of human calcineurin, a ubiquitous Ser/Thr PPP regulated by calcium and...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527731/ https://ncbi.nlm.nih.gov/pubmed/26248042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134569 |
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