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Metamorphic Protein IscU Changes Conformation by cis-trans Isomerizations of Two Peptidyl-Prolyl Peptide Bonds()
IscU from Escherichia coli, the scaffold protein for iron-sulfur cluster biosynthesis and transfer, populates two conformational states with similar free energies and with lifetimes on the order of one second that interconvert in an apparent two-state reaction. One state (S) is structured, and the o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567208/ https://ncbi.nlm.nih.gov/pubmed/23110687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301413y |
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