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Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E(2)
INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with very few effective treatments. The key effector cells in fibrosis are believed to be fibroblasts, which differentiate to a contractile myofibroblast phenotype with enhanced capacity to proliferate and produce ext...
Shranjeno v:
izdano v: | PLoS One |
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Main Authors: | , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527711/ https://ncbi.nlm.nih.gov/pubmed/26248335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135266 |
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