Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E(2)

INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with very few effective treatments. The key effector cells in fibrosis are believed to be fibroblasts, which differentiate to a contractile myofibroblast phenotype with enhanced capacity to proliferate and produce ext...

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Vydáno v:PLoS One
Hlavní autoři: Epa, Amali P., Thatcher, Thomas H., Pollock, Stephen J., Wahl, Lindsay A., Lyda, Elizabeth, Kottmann, R. M., Phipps, Richard P., Sime, Patricia J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527711/
https://ncbi.nlm.nih.gov/pubmed/26248335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135266
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