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Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57(Kip2)
Cleft palate is a common birth defect in humans. Therefore, understanding the molecular genetics of palate development is important from both scientific and medical perspectives. Lhx6 and Lhx8 encode LIM homeodomain transcription factors, and inactivation of both genes in mice resulted in profound c...
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| 出版年: | Hum Mol Genet |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527495/ https://ncbi.nlm.nih.gov/pubmed/26071365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv223 |
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