Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57(Kip2)

Cleft palate is a common birth defect in humans. Therefore, understanding the molecular genetics of palate development is important from both scientific and medical perspectives. Lhx6 and Lhx8 encode LIM homeodomain transcription factors, and inactivation of both genes in mice resulted in profound c...

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Bibliographic Details
Published in:Hum Mol Genet
Main Authors: Cesario, Jeffry M., Landin Malt, Andre, Deacon, Lindsay J., Sandberg, Magnus, Vogt, Daniel, Tang, Zuojian, Zhao, Yangu, Brown, Stuart, Rubenstein, John L., Jeong, Juhee
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527495/
https://ncbi.nlm.nih.gov/pubmed/26071365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv223
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