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Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57(Kip2)
Cleft palate is a common birth defect in humans. Therefore, understanding the molecular genetics of palate development is important from both scientific and medical perspectives. Lhx6 and Lhx8 encode LIM homeodomain transcription factors, and inactivation of both genes in mice resulted in profound c...
Tallennettuna:
| Julkaisussa: | Hum Mol Genet |
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| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527495/ https://ncbi.nlm.nih.gov/pubmed/26071365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv223 |
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