Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57(Kip2)

Cleft palate is a common birth defect in humans. Therefore, understanding the molecular genetics of palate development is important from both scientific and medical perspectives. Lhx6 and Lhx8 encode LIM homeodomain transcription factors, and inactivation of both genes in mice resulted in profound c...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Cesario, Jeffry M., Landin Malt, Andre, Deacon, Lindsay J., Sandberg, Magnus, Vogt, Daniel, Tang, Zuojian, Zhao, Yangu, Brown, Stuart, Rubenstein, John L., Jeong, Juhee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527495/
https://ncbi.nlm.nih.gov/pubmed/26071365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv223
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