Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype

Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially available mice overexpressing phospholamban (Pln(OE)),...

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Bibliografske podrobnosti
izdano v:Dis Model Mech
Main Authors: Fajardo, Val A., Bombardier, Eric, McMillan, Elliott, Tran, Khanh, Wadsworth, Brennan J., Gamu, Daniel, Hopf, Andrew, Vigna, Chris, Smith, Ian C., Bellissimo, Catherine, Michel, Robin N., Tarnopolsky, Mark A., Quadrilatero, Joe, Tupling, A. Russell
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2015
Teme:
Resource Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527296/
https://ncbi.nlm.nih.gov/pubmed/26035394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020859
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