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Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype

Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially available mice overexpressing phospholamban (Pln(OE)),...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Fajardo, Val A., Bombardier, Eric, McMillan, Elliott, Tran, Khanh, Wadsworth, Brennan J., Gamu, Daniel, Hopf, Andrew, Vigna, Chris, Smith, Ian C., Bellissimo, Catherine, Michel, Robin N., Tarnopolsky, Mark A., Quadrilatero, Joe, Tupling, A. Russell
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527296/
https://ncbi.nlm.nih.gov/pubmed/26035394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020859
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