Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance

BACKGROUND: Psoriasis is a chronic disease characterized by the development of scaly red skin lesions and possible co-morbid conditions. The psoriasis lesional skin transcriptome has been extensively investigated, but mRNA levels do not necessarily reflect protein abundance. The purpose of this stud...

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Veröffentlicht in:Genome Med
Hauptverfasser: Swindell, William R., Remmer, Henriette A., Sarkar, Mrinal K., Xing, Xianying, Barnes, Drew H., Wolterink, Liza, Voorhees, John J., Nair, Rajan P., Johnston, Andrew, Elder, James T., Gudjonsson, Johann E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527112/
https://ncbi.nlm.nih.gov/pubmed/26251673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0208-5
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