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Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era

BACKGROUND: Genome-scale studies of psoriasis have been used to identify genes of potential relevance to disease mechanisms. For many identified genes, however, the cell type mediating disease activity is uncertain, which has limited our ability to design gene functional studies based on genomic fin...

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Autori principali: Swindell, William R, Stuart, Philip E, Sarkar, Mrinal K, Voorhees, John J, Elder, James T, Johnston, Andrew, Gudjonsson, Johann E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060870/
https://ncbi.nlm.nih.gov/pubmed/24885462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-27
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