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Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome
To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 in X-inactivation. Xist exon 7 is the second-largest exon with a well-conserved repeat E in eutherian mammals, but its role...
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| Gepubliceerd in: | PLoS Genet |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526699/ https://ncbi.nlm.nih.gov/pubmed/26244333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005430 |
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