Formation of nucleosomes on positively supercoiled DNA.

A transcribing RNA polymerase is thought to generate positive supercoils in front of the advancing transcription complex and negative supercoils behind. We have examined the possibility that positive supercoils might destabilize nucleosomes, facilitating transcription. We show that histone octamers...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Clark, D J, Felsenfeld, G
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07960.x
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