Formation of nucleosomes on positively supercoiled DNA.

A transcribing RNA polymerase is thought to generate positive supercoils in front of the advancing transcription complex and negative supercoils behind. We have examined the possibility that positive supercoils might destabilize nucleosomes, facilitating transcription. We show that histone octamers...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Clark, D J, Felsenfeld, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07960.x
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