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Formation of nucleosomes on positively supercoiled DNA.
A transcribing RNA polymerase is thought to generate positive supercoils in front of the advancing transcription complex and negative supercoils behind. We have examined the possibility that positive supercoils might destabilize nucleosomes, facilitating transcription. We show that histone octamers...
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| Publicado en: | EMBO J |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
1991
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07960.x |
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