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Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometric (LC/ESI-MS/MS) Study for the Identification and Characterization of In Vivo Metabolites of Cisplatin in Rat Kidney Cancer Tissues: Online Hydrogen/Deuterium (H/D) Exchange Study

In vivo rat kidney tissue metabolites of an anticancer drug, cisplatin (cis-diamminedichloroplatinum [II]) (CP) which is used for the treatment of testicular, ovarian, bladder, cervical, esophageal, small cell lung, head and neck cancers, have been identified and characterized by using liquid chroma...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bandu, Raju, Ahn, Hyun Soo, Lee, Joon Won, Kim, Yong Woo, Choi, Seon Hee, Kim, Hak Jin, Kim, Kwang Pyo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526507/
https://ncbi.nlm.nih.gov/pubmed/26244343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134027
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