GATA2(−/−) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment

BACKGROUND: Hematopoiesis is a progressive process collectively controlled by an elaborate network of transcription factors (TFs). Among these TFs, GATA2 has been implicated to be critical for regulating multiple steps of hematopoiesis in mouse models. However, whether similar function of GATA2 is c...

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發表在:Cell Regen
Main Authors: Huang, Ke, Du, Juan, Ma, Ning, Liu, Jiajun, Wu, Pengfei, Dong, Xiaoya, Meng, Minghui, Wang, Wenqian, Chen, Xin, Shi, Xi, Chen, Qianyu, Yang, Zhongzhou, Chen, Shubin, Zhang, Jian, Li, Yuhang, Li, Wei, Zheng, Yi, Cai, Jinglei, Li, Peng, Sun, Xiaofang, Wang, Jinyong, Pei, Duanqing, Pan, Guangjin
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526303/
https://ncbi.nlm.nih.gov/pubmed/26246892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13619-015-0018-7
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