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GATA2(−/−) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment

BACKGROUND: Hematopoiesis is a progressive process collectively controlled by an elaborate network of transcription factors (TFs). Among these TFs, GATA2 has been implicated to be critical for regulating multiple steps of hematopoiesis in mouse models. However, whether similar function of GATA2 is c...

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Detalhes bibliográficos
Publicado no:Cell Regen
Main Authors: Huang, Ke, Du, Juan, Ma, Ning, Liu, Jiajun, Wu, Pengfei, Dong, Xiaoya, Meng, Minghui, Wang, Wenqian, Chen, Xin, Shi, Xi, Chen, Qianyu, Yang, Zhongzhou, Chen, Shubin, Zhang, Jian, Li, Yuhang, Li, Wei, Zheng, Yi, Cai, Jinglei, Li, Peng, Sun, Xiaofang, Wang, Jinyong, Pei, Duanqing, Pan, Guangjin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526303/
https://ncbi.nlm.nih.gov/pubmed/26246892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13619-015-0018-7
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