GATA2(−/−) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment

BACKGROUND: Hematopoiesis is a progressive process collectively controlled by an elaborate network of transcription factors (TFs). Among these TFs, GATA2 has been implicated to be critical for regulating multiple steps of hematopoiesis in mouse models. However, whether similar function of GATA2 is c...

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Dades bibliogràfiques
Publicat a:Cell Regen
Autors principals: Huang, Ke, Du, Juan, Ma, Ning, Liu, Jiajun, Wu, Pengfei, Dong, Xiaoya, Meng, Minghui, Wang, Wenqian, Chen, Xin, Shi, Xi, Chen, Qianyu, Yang, Zhongzhou, Chen, Shubin, Zhang, Jian, Li, Yuhang, Li, Wei, Zheng, Yi, Cai, Jinglei, Li, Peng, Sun, Xiaofang, Wang, Jinyong, Pei, Duanqing, Pan, Guangjin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526303/
https://ncbi.nlm.nih.gov/pubmed/26246892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13619-015-0018-7
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