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Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding

Toll-like receptor-4 (TLR-4) is elevated in skeletal muscle of obese humans, and data from our laboratory have shown that activation of TLR-4 in skeletal muscle via LPS results in decreased fatty acid oxidation (FAO). The purpose of this study was to determine whether overexpression of TLR-4 in skel...

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הוצא לאור ב:	Am J Physiol Regul Integr Comp Physiol
Main Authors:	McMillan, Ryan P., Wu, Yaru, Voelker, Kevin, Fundaro, Gabrielle, Kavanaugh, John, Stevens, Joseph R., Shabrokh, Elika, Ali, Mostafa, Harvey, Mordecai, Anderson, Angela S., Boutagy, Nabil E., Mynatt, Randall L., Frisard, Madlyn I., Hulver, Matthew W.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Physiological Society 2015
נושאים:	Obesity, Diabetes and Energy Homeostasis
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4525328/ https://ncbi.nlm.nih.gov/pubmed/26084695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00139.2015
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Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding

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