Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding

Toll-like receptor-4 (TLR-4) is elevated in skeletal muscle of obese humans, and data from our laboratory have shown that activation of TLR-4 in skeletal muscle via LPS results in decreased fatty acid oxidation (FAO). The purpose of this study was to determine whether overexpression of TLR-4 in skel...

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Dades bibliogràfiques
Publicat a:Am J Physiol Regul Integr Comp Physiol
Autors principals: McMillan, Ryan P., Wu, Yaru, Voelker, Kevin, Fundaro, Gabrielle, Kavanaugh, John, Stevens, Joseph R., Shabrokh, Elika, Ali, Mostafa, Harvey, Mordecai, Anderson, Angela S., Boutagy, Nabil E., Mynatt, Randall L., Frisard, Madlyn I., Hulver, Matthew W.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Obesity, Diabetes and Energy Homeostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525328/
https://ncbi.nlm.nih.gov/pubmed/26084695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00139.2015
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