Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding

Toll-like receptor-4 (TLR-4) is elevated in skeletal muscle of obese humans, and data from our laboratory have shown that activation of TLR-4 in skeletal muscle via LPS results in decreased fatty acid oxidation (FAO). The purpose of this study was to determine whether overexpression of TLR-4 in skel...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am J Physiol Regul Integr Comp Physiol
Κύριοι συγγραφείς: McMillan, Ryan P., Wu, Yaru, Voelker, Kevin, Fundaro, Gabrielle, Kavanaugh, John, Stevens, Joseph R., Shabrokh, Elika, Ali, Mostafa, Harvey, Mordecai, Anderson, Angela S., Boutagy, Nabil E., Mynatt, Randall L., Frisard, Madlyn I., Hulver, Matthew W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2015
Θέματα:
Obesity, Diabetes and Energy Homeostasis
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525328/
https://ncbi.nlm.nih.gov/pubmed/26084695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00139.2015
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