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Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation

Chromosome condensation is a hallmark of mitosis in eukaryotes and is a prerequisite for faithful segregation of genetic material to daughter cells. Here we show that condensin, which is essential for assembling condensed chromosomes, helps to preclude the detrimental effects of gene transcription o...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sutani, Takashi, Sakata, Toyonori, Nakato, Ryuichiro, Masuda, Koji, Ishibashi, Mai, Yamashita, Daisuke, Suzuki, Yutaka, Hirano, Tatsuya, Bando, Masashige, Shirahige, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525155/
https://ncbi.nlm.nih.gov/pubmed/26204128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8815
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