Airway epithelial cell PPARγ modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice

Chronic obstructive pulmonary disease (COPD) is a highly prevalent, chronic inflammatory lung disease with limited existing therapeutic options. While modulation of peroxisome proliferator-activating receptor (PPAR)-γ activity can modify inflammatory responses in several models of lung injury, the r...

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Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Solleti, Siva Kumar, Simon, Dawn M., Srisuma, Sorachai, Arikan, Meltem C., Bhattacharya, Soumyaroop, Rangasamy, Tirumalai, Bijli, Kaiser M., Rahman, Arshad, Crossno, Joseph T., Shapiro, Steven D., Mariani, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525123/
https://ncbi.nlm.nih.gov/pubmed/26024894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00287.2014
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