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Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response

Because therapeutic options are lacking for bronchopulmonary dysplasia (BPD), there is an urgent medical need to discover novel targets/drugs to treat this neonatal chronic lung disease. Metformin, a drug commonly used to lower blood glucose in type 2 diabetes patients, may be a novel therapeutic op...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Chen, Xueyu, Walther, Frans J., Sengers, Rozemarijn M. A., Laghmani, El Houari, Salam, Asma, Folkerts, Gert, Pera, Tonio, Wagenaar, Gerry T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525117/
https://ncbi.nlm.nih.gov/pubmed/26047641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00389.2014
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