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Angiotensin II type 2 receptor ligand PD123319 attenuates hyperoxia-induced lung and heart injury at a low dose in newborn rats

Intervening in angiotensin (Ang)-II type 2 receptor (AT2) signaling may have therapeutic potential for bronchopulmonary dysplasia (BPD) by attenuating lung inflammation and preventing arterial hypertension (PAH)-induced right ventricular hypertrophy (RVH). We first investigated the role of AT2 inhib...

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Detalhes bibliográficos
Main Authors: Wagenaar, Gerry T. M., Sengers, Rozemarijn M. A., Laghmani, El Houari, Chen, Xueyu, Lindeboom, Melissa P. H. A., Roks, Anton J. M., Folkerts, Gert, Walther, Frans J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121644/
https://ncbi.nlm.nih.gov/pubmed/24951776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00345.2013
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