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Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats
Phosphodiesterase (PDE) 4 inhibitors are potent anti-inflammatory drugs with antihypertensive properties, and their therapeutic role in bronchopulmonary dysplasia (BPD) is still controversial. We studied the role of PDE4 inhibition with piclamilast on normal lung development and its therapeutic valu...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349366/ https://ncbi.nlm.nih.gov/pubmed/21949154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00041.2011 |
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