Hepatic De Novo Lipogenesis in Obese Youth Is Modulated by a Common Variant in the GCKR Gene

OBJECTIVE: This study's aim was to evaluate whether the GCKR rs1260326 variant increases hepatic de novo lipogenesis (DNL). SETTING AND DESIGN: To test this hypothesis, 14 adolescents, seven homozygous for the common allele (CC) and seven homozygous for the risk allele (TT), underwent measureme...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Santoro, Nicola, Caprio, Sonia, Pierpont, Bridget, Van Name, Michelle, Savoye, Mary, Parks, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524990/
https://ncbi.nlm.nih.gov/pubmed/26043229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-1587
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