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A Variant in the Glucokinase Regulatory Protein (GCKR) Gene is Associated with Fatty Liver in Obese Children and Adolescents

BACKGROUND: Recently the SNP identified as rs1260326, in the glucokinase regulatory protein (GCKR) was associated with hypertriglyceridemia in adults. Since accumulation of triglycerides in hepatocytes represents the hallmark of the steatosis, we aimed to investigate whether this variant might be as...

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Détails bibliographiques
Auteurs principaux: Santoro, Nicola, Zhang, Clarence K., Zhao, Hongyu, Pakstis, Andrew J, Kim, Grace, Kursawe, Romy, Dykas, Daniel J., Bale, Allen E., Giannini, Cosimo, Pierpont, Bridget, Shaw, Melissa M., Leif, Groop, Caprio, Sonia
Format: Artigo
Langue:Inglês
Publié: 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288435/
https://ncbi.nlm.nih.gov/pubmed/22105854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24806
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