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Hepatic Fat Accumulation Is Modulated by the Interaction between the rs738409 Variant in the PNPLA3 Gene and the Dietary Omega6/Omega3 PUFA Intake

BACKGROUND: A single nucleotide polymorphism (SNP), the rs738409, in the patatin like phospholipase 3 gene (PNPLA3) has been recently associated with increased hepatic steatosis and ALT levels in adults and children. Given the potential role of PNPLA3 in fatty liver development, we aimed to explore...

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Autores principales: Santoro, Nicola, Savoye, Mary, Kim, Grace, Marotto, Katie, Shaw, Melissa M., Pierpont, Bridget, Caprio, Sonia
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357343/
https://ncbi.nlm.nih.gov/pubmed/22629460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037827
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