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A Novel Mouse Model of Left Ventricular Pressure Overload and Infarction Causing Predictable Ventricular Remodelling and Progression to Heart Failure
Mouse surgical models are important tools for evaluating mechanisms of human cardiac disease. The clinically relevant co-morbidities of hypertension and ischemia have not been explored in mice. We have developed a surgical approach that combines transverse aortic constriction (TAC) and distal left a...
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| Publicado no: | Clin Exp Pharmacol Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4524882/ https://ncbi.nlm.nih.gov/pubmed/25311547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12318 |
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