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A Novel Mouse Model of Left Ventricular Pressure Overload and Infarction Causing Predictable Ventricular Remodelling and Progression to Heart Failure

Mouse surgical models are important tools for evaluating mechanisms of human cardiac disease. The clinically relevant co-morbidities of hypertension and ischemia have not been explored in mice. We have developed a surgical approach that combines transverse aortic constriction (TAC) and distal left a...

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書誌詳細
出版年:Clin Exp Pharmacol Physiol
主要な著者: Weinheimer, Carla J., Lai, Ling, Kelly, Daniel P., Kovacs, Attila
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524882/
https://ncbi.nlm.nih.gov/pubmed/25311547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12318
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