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Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation

Mobile bacterial group II introns are evolutionary ancestors of spliceosomal introns and retroelements in eukaryotes. They consist of an autocatalytic intron RNA (a “ribozyme”) and an intron-encoded reverse transcriptase, which function together to promote intron integration into new DNA sites by a...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Truong, David M., Hewitt, F. Curtis, Hanson, Joseph H., Cui, Xiaoxia, Lambowitz, Alan M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524724/
https://ncbi.nlm.nih.gov/pubmed/26241656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005422
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