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Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation

Mobile bacterial group II introns are evolutionary ancestors of spliceosomal introns and retroelements in eukaryotes. They consist of an autocatalytic intron RNA (a “ribozyme”) and an intron-encoded reverse transcriptase, which function together to promote intron integration into new DNA sites by a...

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Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Truong, David M., Hewitt, F. Curtis, Hanson, Joseph H., Cui, Xiaoxia, Lambowitz, Alan M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524724/
https://ncbi.nlm.nih.gov/pubmed/26241656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005422
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