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Genetic and Biochemical Assays Reveal a Key Role for Replication Restart Proteins in Group II Intron Retrohoming

Mobile group II introns retrohome by an RNP-based mechanism in which the intron RNA reverse splices into a DNA site and is reverse transcribed by the associated intron-encoded protein. The resulting intron cDNA is then integrated into the genome by cellular mechanisms that have remained unclear. Her...

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Sonraí Bibleagrafaíochta
Main Authors: Yao, Jun, Truong, David M., Lambowitz, Alan M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636086/
https://ncbi.nlm.nih.gov/pubmed/23637634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003469
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